Porous Silk Fibroin Microspheres Sustainably Releasing Bioactive Basic Fibroblast Growth Factor
نویسندگان
چکیده
منابع مشابه
Silk fibroin sponges with cell growth-promoting activity induced by genetically fused basic fibroblast growth factor.
Transgenic silkworm technology has enabled the biological properties of silk fibroin protein to be altered by fusion to recombinant bioactive proteins. However, few studies have reported the fabrication of genetically modified fibroin proteins into three-dimensional spongy structures to serve as scaffolds for tissue engineering. We generated a transgenic silkworm strain that produces fibroin fu...
متن کاملSilk Fibroin Based Porous Materials
Silk from the Bombyx mori silkworm is a protein-based fiber. Bombyx mori silk fibroin (SF) is one of the most important candidates for biomedical porous material based on its superior machinability, biocompatibility, biodegradation, bioresorbability, and so on. In this paper, we have reviewed the key features of SF. Moreover we have focused on the morphous, technical processing, and biocompatib...
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The objective of the present study is to investigate the possibility of preparing pure protein microspheres from regenerated silk fibroin (RSF). It is found that RSF microspheres, with predictable and controllable sizes ranging from 0.2 to 1.5 mm, can be prepared via mild selfassembling of silk fibroin molecular chains. The merits of this novel method include a rather simple production apparatu...
متن کاملExploring the Mechanism of Microarteriogenesis in Porous Silk Fibroin Film
Purpose. Based on the experiment of the microarteriogenesis that is associated with angiogenesis during tissue repair process in porous silk fibroin films (PSFFs), we investigate the characteristics of micro-arteriogenesis and explore its mechanism. Methods. After the porous silk fibroin materials are implanted into the back hypodermal tissue of SD rats, the arteriole development and the morpho...
متن کاملPorous Materials Based on Bombyx Mori Silk Fibroin
Bombyx mori silk fibroin (SF) is one of the most important fibers among biomedical porous materials due to its superior machinability, and biocompatibility. It is also chosen for its biodegradability and bioresorbability. It is a protein-based fiber. In this paper, we have reviewed the key features of SF. Moreover we have focused on the morphous, technical processing and biocompatibility of SF ...
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ژورنال
عنوان ژورنال: Materials
سال: 2018
ISSN: 1996-1944
DOI: 10.3390/ma11081280